In the world of regenerative medicine, progress never stops. Following the emergence of PRP (platelet-rich plasma) and PRF (fibrin-rich plasma), the Spanish company Meta Cell Technology (MCT) took the next step beyond the standards. MCT created a system for photothermal biomodulation of autologous plasma to achieve even better results.
MCT is a system consisting of two certified medical devices (the MCT Unit and the MCT Kit) designed to enhance autologous products such as PRP (platelet-rich plasma) while releasing the patient’s exosomes in a single session. By utilizing photothermal biomodulation, the MCT system maximizes the number of available exosomes, ensuring optimal results.
Using this advanced technology, the MCT system provides high-quality exosomes naturally, enhancing therapeutic potential.
The use of MCT in regenerative medicine has enabled the development of three new autologous products—MCT Plasma, MCT Exosomes, and EXO-TECH—the first bioimplant containing exosomes
MCT Plasma is an advanced form of PRP. While traditional PRP harnesses the natural regenerative capacity of your platelets, MCT Plasma takes it a step further by activating and optimizing the plasma through a patented technology called photothermal biostimulation.
Photothermal biostimulation improves communication between cells and significantly accelerates the release of anti-inflammatory proteins and regenerative growth factors. It also reduces the presence of pro-inflammatory cytokines—accelerators of aging.
At its core, MCT Plasma performs personalized cellular optimization, using light and heat to extract the maximum healing potential from your own body.
Autologous plasma treated with photobiomodulation and thermal biomodulation stimulates platelets and accelerates the release of growth factors, leading to faster and better results.
Release of growth factors
Platelets stimulated by a photothermal method release a greater amount of growth factors in a controlled and sustained manner, resulting in a more physiological effect.
Photothermally stimulated plasma contains fewer pro-inflammatory cytokines and has a more physiological profile. It also improves the platelet activation profile by reducing VASP and increasing p-38 phosphorylation. Cold treatment primes the platelets and facilitates their reactivity after injection.
Cold enhances platelet kinetics after activation, not before, and slows down clot formation. The thinner plasma and the sensation of a cool liquid make the procedure significantly more comfortable.
Photothermal biomodulation stimulates cellular metabolism and enhances ATP synthesis
Light offers a non-invasive and non-toxic way to stimulate cellular metabolism. Ultimately, the energy absorbed by the mitochondria boosts cellular ATP production. The photothermal stimulation of PRP creates a modern regenerative preparation.
It achieves better clinical results thanks to the prolonged and sustained release of growth factors and the reduced content of pro-inflammatory cytokines.
Just as with light, there is a vast body of evidence confirming the effectiveness and safe use of heat. Thermal stimulation prepares platelets to function more actively and efficiently, increases their reactivity, and leads to the appearance of numerous activation markers. This enhanced platelet function also leads to an increase in growth factors.
Since thermal stimulation delays clot formation and prepares platelet aggregation only after activation, this results in a less dense regenerative product, improving clinical outcomes and ensuring more comfortable injection.
The ability to obtain exosomes of animal or plant origin marked the beginning of a new era that enhances the efficacy of therapies in regenerative medicine. The MCT System takes a step forward by providing autologous exosomes for medical injection, leading to significantly improved results.
MCT Exosomes are microscopic extracellular proteins released by your cells during the MCT process. They carry powerful regenerative instructions, signaling proteins, RNA, and enzymes that stimulate healing and tissue repair in neighboring cells. Exosomes are the communication foundation of regenerative aesthetics, enabling improved skin repair and renewal. In the MCT process, these exosomes are selectively amplified to increase their therapeutic potential. They act as powerful signals, encouraging your skin to repair itself more intelligently, not more intensely.
Unlike non-autologous exosomes, which can be grown in a laboratory or derived from plants, MCT exosome therapy is autologous—created from your own body—which drastically reduces the risk of a reaction or rejection. It is unique because MCT exosomes are specifically tailored to your cellular code. By reinjecting these enhanced, bioactivated exosomes into your skin, you don’t just hydrate or stimulate it—you reprogram your skin to behave like younger skin.
The MCT system delivers autologous exosomes that are natural and compatible with your body.
Source: | Cells and tissues from the same patient |
Level: | Medical. |
Certification: | CE/MDR |
Directions for use:
| For injection.
|
Contents:
| Reliable. |
Results: | Significant. |
Source: | Animals, plants |
Level: | Cosmetic: |
Certification: | Cosmetic: |
Directions for use:
| For external use.
|
Content: | Unclear. |
Results: | Unclear: |
Photothermal biostimulation induces a controlled and sustained release of growth factors from platelets, thereby achieving a more physiological effect.
The photothermal effect on cells and platelets stimulates the release of exosomes, leading to improved regenerative outcomes.
Photothermal biomodulation stimulates cellular metabolism and enhances ATP synthesis
Blue light stimulation enhances the therapeutic effect. Exposure to blue light increases microRNA levels and enhances the proangiogenic potential of MSCs. Blue-opsin phototransduction is an invaluable tool for enhancing the regenerative potential of cells.
Temperature increases the frequency of fusion events between exosomes and the cell membrane. The kinetics of exosome release are faster at higher temperatures. Temperature reduces the number of attached exosomes.
Exo-Tech represents a new class of autologous bioimplants designed to provide structural support and a sustained regenerative effect. By combining platelet-poor plasma (PPP) with PRP enriched with exosomes extracted from platelets via the MCT System®, Exo-Tech creates a viscoelastic injectable matrix that combines mechanical lifting with biological regeneration.
Exo-Tech provides a structured protein matrix that acts as a local reservoir, gradually releasing exosomes and growth factors over time—thereby prolonging regenerative activity in the target area.
The scaffold acts as a local reservoir, allowing for the gradual release of exosomes and growth factors, which prolongs their regenerative activity.
The scaffold provides structural support, while exosomes transmit biological signals that activate fibroblasts, stimulate collagen production, and improve dermal architecture.
The protein network protects exosomes from enzymatic degradation and premature elimination.
The use of plasma derived from the patient ensures complete biocompatibility without the use of foreign materials or synthetic polymers.
Exo-Tech acts as a next-generation biostimulating implant that combines structural support with signaling to restore skin quality from within.
MCT PRP is a comprehensive clinical protocol that includes:
The result is anti-inflammatory, regenerative skin therapy with excellent hydration, improved texture, increased collagen density, and a minimal recovery period.
Although PRP therapy remains indispensable for certain conditions, exosome therapy offers a broader regenerative effect. PRP focuses on growth factors; while exosomes expand the scope to include cell signaling, modulation of inflammation, and restoration of the extracellular matrix.
In clinical settings, patients report: Incorporating exosomes into PRP via the MCT method combines the best of both worlds and exponentially multiplies their benefits:
Microneedling is one of the most effective delivery methods for MCT plasma and exosomes. By creating controlled micro-injuries in the skin, microneedling opens the path for these enriched bio-signals to penetrate into the deeper layers of the tissue, where collagen synthesis and cellular regeneration begin. This combination therapy is painless, safe, and offers visible improvement in just two weeks for:
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